Aspadol ER 200 mg

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Product Summary

Offer Price $ 1.52 per pill.
You save Save Up to $ 10 per order.
Active Ingredient Tapentadol 200 mg
Pill Appearance Blue Tablet
Drug Class Opioid pain medication
Country of Origin India
Manufacturer Signature Pharmaceuticals Ltd.

What Is Aspadol 200 Mg?

Aspadol Extended Release (ER) 200 tablet is a pain medication prescribed for moderate to severe pain in adults. In 2008, the FDA approved the centrally-acting opioid painkiller Tapentadol under the brand name Aspadol. Its dual mechanism of action offers relief from a broad range of body pains within 30 minutes.

Aspadol extended-release (ER) tablets are different from immediate-release (IR) formulations based on their ability to disintegrate. The ER medications are formulated to gradually release the active ingredient (tapentadol) into the system. This provides extended pain relief for up to 12 hours, significantly longer than Tapentadol or Aspadol IR tablets, which offer relief for only 4 to 6 hours.

List Of Ingridients

Aspadol ER 200 mg has four main inactive ingredients in addition to its active ingredient, Tapentadol. These are alpha-tocopherol (vitamin E), hypromellose, polyethylene glycol, and polyethylene oxide.

The film coating of the tablet contains polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, and the colorant FD&C Blue #2 aluminum lake.

Aspadol ER 200mg Uses

Aspadol 200 mg tablets are recommended for severe and persistent pain in adults that require extended treatment. It is approved for treating moderate to severe acute pain associated with lower back pain, osteoarthritis pain, postoperative pain, and fibromyalgia. It is also prescribed for diabetic neuropathy, which requires round-the-clock pain relief.

Benefits Of Aspadol Tablets

  • It has a quicker onset of action and works within 30 minutes of intake.
  • Aspadol is one of the most affordable and effective Tapentadol brands available in the market.
  • It is a well-tolerated medication with a lower incidence of gastrointestinal side effects compared to traditional opioid pain medications.
  • The Extended-Release tablets have a prolonged effect and need to be taken only twice daily.

Working Mechanism Of Aspadol 200mg

Aspadol 200 tablets bind to the brain receptor, which helps reduce the feeling of pain. It also stops the reabsorption of a chemical called norepinephrine, which helps to further block pain signals.

The extended-release tablet of Aspadol releases the medication slowly over time, providing steady pain relief without the need to take the pill as often.

Dosage Guidelines

For moderate to severe acute pain, 200 mg of Aspadol ER can be taken every 12 hours.

The maximum dose of Aspadol ER tablets is 500 mg daily.

Missed Dose

If you missed a dose of Aspadol 200 mg, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Alternative Dose

Beginners are recommended to start with a lower dose of Tapentadol, such as Topcynta 50 mg or Aspadol 100 mg. Depending on the severity of the pain, the dose can be increased to Tapaday 200 mg.

Note- It is essential to note that the above suggested alternative doses are immediate-release formulas that will work for up to 6 hours and require multiple doses. So, any change in the formulation and dosage strength must be done after consulting a doctor.

Directions Of Use

  • Swallow the Aspadol 200 mg tablet with water.
  • Crushing or chewing the Aspadol 200 tablet can result in the release of the active compound at a higher level than recommended, leading to an overdose.
  • Take the ER tablet at the same time for better results.
  • People with nausea can take the medication with food.
  • Avoid abrupt discontinuation without consulting a doctor to prevent withdrawal symptoms.

Note- Always follow the directions on your prescription level and your doctor’s advice while taking Aspadol tablets.

Side Effects Of Aspadol 200

The common side effects of Aspadol ER tablets include dizziness, Nausea, dry mouth, drowsiness, and tiredness.

Contact a doctor immediately if you experience-

  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Agitation
  • Hallucinations
  • Heavy sweating
  • Feeling overheated.

Taking Aspadol 200 mg tablets with other opioid medicines or other central nervous system depressants can cause severe drowsiness, decreased awareness, and even coma in severe cases. It can cause serious, life-threatening respiratory issues in older adults, especially with chronic breathing disorders.

Precautions And Warnings


Prolonged use of Aspadol ER 200 during pregnancy can cause opioid withdrawal syndrome in the baby.


It is not recommended to breastfeed while taking Aspadol ER, as it can affect the growth and development of the infant.


Do not drive or operate heavy machinery while taking Aspadol ER 200 mg tablet, as it can cause dizziness and drowsiness.


Taking Aspadol ER with alcohol can cause an overdose by increasing the levels of the drug in the blood.

Accidental IngestionAccidental Ingestion

Accidental ingestion of a single dose of Aspadol ER 200 tablet can result in an overdose. In such cases, consult a doctor immediately.

Discuss With Your Doctor

Before taking the Aspadol ER tablet, inform your doctor if you have a history of-

  • Problems urinating
  • Head injury
  • Seizures
  • Kidney and Liver disorders
  • Mental health problems
  • Thyroid problems
  • Addiction and substance abuse.

Storage And Disposal

Proper disposal involves flushing the medication down the toilet or wrapping it in o be kept away from direct sunlight and moisture.

Dispose of the medication properly by flushing it down the toilet or first wrapping it in a piece of paper before putting it in the trash can.

Drug Interaction Of Aspadol 200

The intake of Aspadol 200 tablets with other medication (both over-the-counter and prescription) and supplements can cause drug interaction. It can result in a higher risk of side effects and lower effectiveness.

The table below lists medications and supplements that should be taken with Aspadol 200 tablets.

Moderate Drug Interaction Severe Drug Interaction
Albuterol Asenapine
Belladonna Buspirone
Clidinium Dolasetron
Dopamine Esketamine
Evening Primrose Gepirone
Isoproterenol Lemborexant
Methoxamine Meperidine
Naloxone Naratriptan
Ritodrine Paliperidone
Tolcapone St. John’s Wort

Apart from the medicines listed here, it is crucial to inform your doctor before taking any other medicine or supplement with Aspadol 200.

Shipping Policy

All medications are shipped from Mumbai, India, once the shipping address and payment are confirmed. All our orders are processed and shipped within 24 hours of payment verification. A tracking number is sent to the customer against their shipment to help track the package during transit. 

All medications are shipped with the utmost diligence; in the event of damaged or missing products, the Online Pills Store will reship the order.

For more detailed information, visit our shipping policy page. 

Delivery Time Frame

The medications may take 15 to 20 days to get delivered as they are shipped from India. We offer express delivery on our pain medications (Tapentadol and Soma pills), with a delivery time frame of 5 to 7 days.

Return And Refund Policy

To be eligible for a return, the following conditions should be met:. 

  • The medicines should be in their original packaging 
  • If a return is initiated within 24 hours of receiving the package,. 
  • We only accept returns if the package or product is damaged in transit. Or if the wrong product was delivered. 

How do you initiate a return?

To initiate a return or refund, contact our customer support team at [email protected]. You need to send a clear image and description of the damaged product or package to our team, who will then approve your request and assist you further with the return process.


Once we receive the medication or package, our team will start processing your refund, which should appear in your bank account within 48 to 72 days. 

For additional information, check our Return and Refund Policy page.

Additional information


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+ What is Aspadol ER 200 mg used for?

Aspadol ER is used to treat moderate to severe chronic pain associated with fibromyalgia, diabetic neuropathy, and postoperative pain.

+ Can I order Aspadol 200 in the USA?

Yes, you can order Aspadol 200 in the USA from

+ Can Aspadol 200 be used for short-term pain management?

Yes, Aspadol 200 mg tablets are advised for short-term management of pain.

+ How long does it take for Aspadol 200 mg ER to start working?

It takes about 30 minutes for 200 tablets of Aspadol ER to start working.

+ Will I get any benefits from reordering Aspadol 200 tablets?

Yes, we offer additional free pills on all reorders of Aspadol 200 mg.

+ Is Aspadol ER 200 addictive?

Yes, long-term use of Aspadol 200 mg can cause addiction and dependency.

+ What is the Aspadol or Tapentadol 200 mg price?

The cost of Aspadol 200 mg is $ 1.52 per pill at an online pills store.

+ Can I buy aspadol without a prescription?

No, Aspadol 200 mg is a prescription medication and is not available over the counter without a medical prescription. However, offers Aspadol 200 mg tablets without a prescription to make it convenient and accessible to our customers.