Soma Vs. Flexeril- Choose the right pain medication

Soma Vs. Flexeril- Choose the right pain medication

Soma vs. Flexeril is a comparative study of both muscle relaxants based on various factors, and according to our findings, Soma is the better choice than Flexeril because of its quick onset of action, price, and rating.

Are you suffering from muscle discomfort and pain? You are not alone. Millions of individuals in the United States suffer from muscle tension, strain, spasms, and other muscle-related problems and often turn to medications like Carisoprodol (Soma) and cyclobenzaprine (Flexeril). But among the two available options, Soma vs. Flexeril, it could be tough to decide which is right for you.

In this context, we have covered specific details about Soma vs. Flexeril so that it becomes easy for you to decide which one to opt for. 

So, Soma vs. Flexeril, which is stronger, let's find out.

Soma And Flexeril: An Overview

What is Soma?

Carisoprodol, sold under Soma, is used for musculoskeletal pain. In 1959, the FDA approved carisoprodol for medical use [1]. 

What is Flexeril?

Cyclobenzaprine (Flexeril) is an effective muscle relaxant to treat muscle spasms. The Food and Drug Administration approved this medication in 1977.

Differences And Similarities Between Soma And Flexeril


Flexeril and Soma's comparison is quite interesting because both medicines are similar. In the table below, we have compared both drugs based on various factors.




Drug class 

Skeletal muscle relaxant

Skeletal muscle relaxant

Prescription status

Prescription-only drug

Prescription-only drug

Available dosage 

250 mg and 350 mg

5 mg, 7.5 mg, and 10 mg.

The onset of action

30 minutes

1 hour

Drug form

Oral pill

Oral pill

Generic name




The cost of a Soma pill is $1.34 per pill

$5 per pill


9 out of 10 on the website

5.9 out of 10 on the website

Duration of action

4-6 hours

4-6 hours

Soma Versus Flexeril: Understanding The Key Differences In Their Uses

Flexeril Vs. Soma for Chronic Back Pain Relief

Back pain is a type of pain that is felt in the back, typically near the spinal cord. It can be classified as middle back pain, neck pain, or lower back pain based on the segment affected. When the back pain lasts for three months or more, it is termed chronic back pain.

Both Soma and Flexeril are effective for treating chronic back pain, but the effects of Soma last for almost seven days, whereas the effects of Flexeril last for only around four days.

Therefore, Soma is superior to Flexeril in treating chronic back pain [2] [3].

Soma vs. Flexeril for Fibromyalgia

Pain from Fibromyalgia can impact your quality of life, making it difficult to perform everyday tasks.

Fibromyalgia is a long-lasting condition that causes tenderness and pain throughout the body, insomnia, and fatigue [4].

Soma or Carisoprodol can help reduce pain caused by muscle spasms and pain associated with Fibromyalgia.

According to a small study completed in 1989, Soma effectively improved sleep quality, reduced pain, and increased feelings of well-being in people with fibromyalgia. In addition, it was found that Acetaminophen, Carisoprodol, and caffeine were effective as a treatment for fibromyalgia [5].

On the other hand, Flexeril can improve sleep and reduce pain in cases of fibromyalgia.

A study published in the year 2011 showed that Flexeril showed promise for the treatment of fibromyalgia.

A total of 29 patients with fibromyalgia were given low doses of cyclobenzaprine or a placebo, and among those that were given cyclobenzaprine, sleep time increased from 5.4 hours to 6.4 hours, and pain decreased to 26% in those who took Flexeril compared to 18% in the control group.

There was also a significant reduction in depression and tenderness in those who took Cyclobenzaprine [6].

Soma vs. Flexeril for Multiple Sclerosis

Multiple sclerosis is a condition that can affect the spinal cord and brain, causing a wide range of undesirable symptoms, including vision problems, sensation or balance, and leg or arm movement. It is a chronic condition (long-term) that is occasionally mild but can sometimes cause severe disability. 

Some symptoms of Multiple sclerosis are muscle spasms, stiffness and weakness, mobility problems, numbness and tingling, fatigue, etc.

 Soma muscle relaxants and Flexeril are often prescribed for patients with Multiple Sclerosis because these muscle relaxants help with some of the common symptoms of Multiple sclerosis, such as pain and muscle spasms [7].

Soma vs. Flexeril for Muscle Strains and Sprains

A muscle sprain is defined as a torn or stretched ligament, whereas a muscle strain is a torn or stretched muscle or tendons.

Carisoprodol and Cyclobenzaprine, in conjunction with physical therapy, rest, and other treatments, are used to relax muscles and relieve discomfort and pain caused by muscle sprains and strains.

Both medicines belong to the class of drugs known as skeletal muscle relaxants and work by relaxing the muscles by acting on the nervous system and brain.

Carisoprodol vs. Cyclobenzaprine: Safety and Long-Term Use

The long-term use of Soma is unsafe and is not recommended for use over three weeks because taking it over three weeks can cause abuse.

Anyone addicted to Soma will begin to manifest specific behavioral changes, such as 

Crime, strained relationships, thoughts of suicide, mood changes, consistent attempts to procure prescriptions, declining work performance, and withdrawal from previously enjoyed activities.

People abusing Soma may experience various symptoms of withdrawal, such as insomnia, headaches, anxiety, diarrhea, nausea and vomiting, and abdominal cramping [8]. 

Flexeril should be used for two to three weeks because its effectiveness for long-term use is unknown [9].

An individual might abuse Cyclobenzaprine to feel mildly euphoric, relaxed, or sedated, and long-term use of the drug can lead to physical dependence; a person taking the drug at higher doses due to pain can become familiar with the presence of the drug in the body and can develop an addiction as a result.

Additionally, people using Flexeril may experience mild withdrawal symptoms if the drug is used in high doses.

Some of the signs that indicate someone may have cyclobenzaprine addiction are 

  • Taking Flexeril after it's no longer needed.

  • Faking symptoms to get a Flexeril prescription

  • Sudden changes in behavior, hygiene, and physical appearance

  • Spending the majority of the time thinking about the drug

  • Constantly using the medication [10]

Common Cyclobenzaprine withdrawal symptoms include anxiety, nausea, headache, fatigue, discomfort, chills, and fever [11].  

Soma vs. Flexeril- Comparison of their side effects

Some possible side effects of Flexeril are dry mouth, headache, blurred vision, stomach pain, drowsiness, fatigue, loss of appetite,  nausea, muscle weakness, gas, diarrhea, and constipation.

On the other hand, some possible adverse events of Soma's muscle relaxers are drowsiness, agitation, nervousness, dizziness, tremors, headache, irritability, insomnia, blurred vision, depression, upset stomach, nausea, and vomiting [12].

Points To Know Before The Intake Of The Soma Or Flexeril

Before taking any muscle relaxants, follow these points to avoid side effects. The points are as follows:

  • You should not take Soma 350 mg or Flexeril if you’re above 65 years of age.

  • Avoid alcohol while on the medication.

  • Pregnant or lactating women should not take Carisoprodol or Cyclobenzaprine without consulting their healthcare professional.

  • It is advisable to seek medical advice if you have previously experienced any side effects from any medications.

  • Drug intake while on the Soma or Flexeril dose is highly not advisable.

  • Do not overdose on the medicines.

  • Avoid the intake of Flexeril or Soma dose if you are on some other medication. It may cause side effects to the body.

Flexeril Vs. Soma- Drug Interactions

A drug interaction is a reaction between two drugs or drugs and a beverage, food, or supplement.

Flexeril has potential interactions with CNS antidepressants, alcohol, opioids, allergy medications, and sleeping pills, whereas Soma can interact with alcohol, narcotics, benzodiazepines, and barbiturates [13].

A Comparison Of Effectiveness For Muscle Pain Relief In Elderly Patients: Soma Vs. Flexeril

One of the essential pharmacokinetic changes associated with aging is decreased renal elimination of drugs; therefore, Soma and Flexeril should not be taken by older adults because they are not as effective or safe and may cause serious side effects [14] [15] [16].

Soma vs. Flexeril- Conclusion

Soma and Flexeril are commonly prescribed muscle relaxants to help alleviate muscle discomfort and pain. Now, you must be wondering about Soma or Flexeril. Which one to choose?

Based on our findings, if we had to suggest one medicine out of the two, it would be the soma pill, as it has a  quick onset of action and has a rating of 9 out of 10 on the website However, we do not suggest taking Soma medication for muscle discomfort without consulting your doctor. 

Soma is also an affordable choice of muscle relaxant. A similar comparative study between Soma and Robaxin further confirms it to be more pocket-friendly.

If you are wondering how Soma muscle relaxers differ from opioid medications or which is a better pain treatment option, then we recommend you go through our Carisoprodol vs Tramadol blog for a better understanding of the topic. 


Yes, Flexeril and Soma are the same. Both act as muscle relaxers to fight body aches.

The Muscle relaxants work effectively by blocking the body’s ache sensation to reach the brain. We human beings react to any sensation once it is reached to the brain. The Carisoprodol blocks the nerves that send signals to the brain about any sensation.

Muscle relaxants are usually used for short-term body aches. Some examples of short-term aches are cuts, tooth decay, headache, post-operation troubles.

Yes, Soma pills are effective for long-term use. But it is not advisable for the intake of any medication for the entire life. Muscle relaxants should preferably be taken for a shorter period of time.

No, You cannot take two muscle relaxants at the same time. One dose of Carisoprodol is effective for 10 to 12 hours. After that, it may cause adverse effects on the body.

Comparison is quite tough as there are plenty of muscle relaxers. But, unfortunately, all the muscle does the same thing, blocking the nervous system for the ache sensation to reach the brain.

Yes, Tramadol is a muscle relaxer that does the same work as Soma or Flexeril, blocking the nervous system for the ache to reach the brain.

The muscle relaxers work in the human body for 10 to 12 hours.

Both Flexeril and carisoprodol are effective muscle relaxants but Carisoprodol has an average rating of 9 out of 10 on the website whereas Flexeril has an average rating of 5.9 out of 10 on the same website making carisoprodol better.

Yes, because some of them are muscle relaxants.

Yes, Soma works by relaxing the muscles.

According to the ratings on, Soma is stronger than Flexeril.


  1. Carisoprodol, wikipedia

  2. Muscle Relaxants in the Treatment of Acute Low Back Pain, healthcentral

  3. Cyclobenzaprine and back pain: A meta-analysis, jamanetwork

  4. What is Fibromyalgia? - Symptoms & Treatment | NIAMS

  5. Soma (Carisoprodol) for Fibromyalgia, myfibroteam

  6. Flexeril (Cyclobenzaprine) for Fibromyalgia, myfibroteam

  7. Multiple Sclerosis (MS) Treatments, healthline

  8. Effects of Soma Use: Short-Term, Long-Term, Side Effects, and Treatment, drugabuse

  9. Long-term Use of Cyclobenzaprine for Pain: A Review of the Clinical Effectiveness, NCBI

  10. Flexeril Addiction And Abuse, addictioncenter

  11. Cyclobenzaprine Addiction: Side Effects, Detox, Withdrawal, and Treatment, novarecoverycenter

  12. Flexeril Vs. Soma, rxlist

  13. Cyclobenzaprine (Flexeril) Uses, Side Effects, & Risks, lagunatreatment

  14. Cyclobenzaprine, medlineplus

  15.  Carisoprodol, medlineplus.

  16. Pharmacokinetics in Older Adults, merckmanuals

Author’s Note

We strive to provide reliable and accurate health information; thus, the content on our blogs is based on thorough research from reputable papers and journals. Our team relentlessly keeps updating the information on our blogs and articles to ensure it is always up to date with the latest medical research and developments. We advise all our readers to seek advice from a qualified healthcare professional before taking any medication or healthcare product mentioned on our blog or website.


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