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Agnes Smith

Post Uploaded Date : January 29, 2025 Last Updated Date : June 12, 2025
does-pregabalin-cause-hair-loss
Yes, Pregabalin might cause temporary hair loss and is considered a rare side effect of the tablet. There are different influential factors caused by the medication, such as stress, hormonal changes, and nutritional deficiencies, that might lead to hair loss.

Pregabalin is a medication that treats anxiety, nerve pain, and epilepsy. However, it can cause a range of side effects. Certain concerns have been raised among some patients, and reports have been found regarding hair loss. Hair loss is one of the most frequently discussed side effects associated with Pregabalin. In this blog, we will explore the idea of whether there is a direct link between Pregabalin and hair loss, the reasons behind it, and how to mitigate the effects of the tablet.

What Is Pregabalin?

Pregabalin is a commonly used medication that is used for the treatment of conditions such as nerve pain, fibromyalgia, generalized anxiety disorder (GAD), and certain types of seizures. It is sold under different brand names such as Nervigesic and Lyrica.

Pregabalin generally works by affecting the way nerves send signals to the brain, helping to reduce pain. 

To know the working mechanism of Pregabalin in detail, do check our blog page on this subject. 

How Does Pregabalin Is Linked With Hair Loss?

Hair loss due to Pregabalin is not a common side effect. However, there have been certain reports that state people are suffering from hair loss due to pregabalin. There are certain possible explanations that are cited below:

Hormonal Effects

Certain medications can affect hormone levels. This, in turn, can impact hair growth. Pregabalin might affect hormones and the overall body’s balance, which might contribute to hair thinning or loss.

Individual sensitivity

Some individuals may be sensitive or allergic. The components present in pregabalin may cause allergies that could lead to hair loss.

What Does The Research Say?

Many clinical studies and rules state the adverse effects of hair from the use of  Gabapentin or Pregabalin. However, there are specific case reports that mention hair loss as a side effect of Gabapentin.

A certain case report states that a 28-year-old woman was prescribed a high dosage of Gabapentin for extreme neuropathic pain from a past trauma. After following a treatment for one week, the patient suffered from significant patchy hair loss.

Another case report states that a patient experienced a certain hair loss after the use of Pregabalin to a certain extent. The hair loss reversed when the person stopped using the medication.

However, it is important to note that the case reports are for informative purposes.

Other Side Effects Of Pregabalin

Other Side Effects Of Pregabalin

Pregabalin is a medication that might cause you a range of side effects.

Some of the common side effects include:

  • Fatigue.
  • Dizziness or drowsiness.
  • Blurred vision.
  • Dry mouth.
  • Headache.
  • Sudden mood changes.
  • Difficulty in concentrating or certain memory problems.
  • Swelling.
  • Severe allergic reactions.
  • Severe dizziness or fainting.
  • Muscle pain, tenderness or weakness.
  • Weight gain.

To explore more about weight gain due to the medication, visit the blog Pregabalin and weight gain. 

Always consult a medical professional if you experience any unusual symptoms or side effects.

How To Reverse Hair Loss from Pregabalin?

There are certain tips to reverse hair loss due to Pregabalin, as stopping or switching the medication is always an option.

Diet and Supplements:

Vitamins and mineral supplements can help alleviate symptoms of hair loss. It is because vitamins and minerals are essential for cell growth and function. Low levels of minerals and vitamins may contribute to hair loss.

Some of the vitamins and minerals that can contribute to hair loss are:

  • Vitamin D
  • Vitamin C
  • Iron

People with a deficiency can take a supplement to boost their levels, which may help the hair grow back. Additionally, people may also incorporate certain foods rich in vitamins and minerals into their regular dietary plan.

Minoxidil topical solution:

Minoxidil is a treatment solution that helps with hair loss. It is applied directly to the scalp and works by improving blood flow to the hair follicles, thereby promoting hair growth.

Pumpkin seed oil:

Pumpkin seed oil is used to reduce the 5-alpha reductase, an enzyme that contributes to hair loss.

In a 2019 mouse study, it was found that topical application of many fatty acids present in pumpkin seed oil can promote hair growth.

As such, people can use it as a remedy or alternative option for hair growth.

Head massage:

There are some studies that suggest that with regular head massages, you can grow your hair thicker. Massages are also known to reduce stress.

In a study by Taro Koyama et al., it was found that scalp massages can apply gentle pressure to the skin on the head, which helps to improve hair thickness.

You can give yourself a scalp massage by using a massage tool or simply using your fingers.

In another study by Celalletin Turgut and Alparslan Ali, it was found that hair loss stopped completely after they stopped the use of Pregabalin within 15 days.

However, it is important to note that the individual reactions can vary. Therefore, proper consultations with the doctor are required.

Potential Alternative Options For Treating Hair Loss

There are different alternative options to Pregabalin that depend on the condition you are using it for. Some of the options are given below:

  • Gabapentin- It is a medication that is often used for purposes such as nerve pain and seizures.  This works similarly to pregabalin but might have a slightly different effect or side-effect profile for some people.
  • Duloxetine (Cymbalta)- It is an antidepressant that treats nerve pain, especially for conditions such as diabetic neuropathy or fibromyalgia. This works by increasing the levels of serotonin and norepinephrine in the brain.
  • Amitriptyline- It is a tricyclic antidepressant that is often prescribed for nerve pain, and it also works as a mood stabilizer. This also helps with sleep problems associated with pain or anxiety.
  • Carbamazepine is used for the treatment of pain, trigeminal neuralgia, and for controlling seizures.
  • Topiramate- It is primarily an anticonvulsant that helps treat seizures and also helps prevent migraine. It can also sometimes be used for nerve pain.
  • Cyclobenzaprine- It is a muscle relaxant that is sometimes used as an off-label use for nerve pain.

Conclusion

There are several side effects associated with Pregabalin. Hair loss is not commonly listed. Some individuals have reported a certain amount of hair loss while taking the medication. Therefore, it is important to recognize the side effects that can significantly vary from person to person. Additionally, you should note that hair loss can also arise from different factors such as stress, hormonal changes, nutritional deficiencies, or genetics.

FAQs

Is Hair Loss From Pregabalin Permanent?

No, hair loss from Pregabalin is generally considered temporary.

Can hair loss due to Gabapentin be reversed?

Yes, hair loss due to the medication can be reversed.

How long does Pregabalin take to cause hair loss?

Generally, the time taken by Pregabalin to cause hair loss is different from person to person. It might be visible in a few weeks to a few months.

References

  1. Does Gabapentin or Pregabalin cause hair loss, struthealth.com
  2. How to reverse hair loss from medication, medical news today.
  3. Does Gabapentin cause hair loss: What you need to know, hims.com
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